New Example of Acyl Cleavage of Benzoyl-1,1,1-trifluoroacetone in a Three-Component Synthesis of 4-Aryl-2-thioxo-6-phenyl-1,2- dihydropyridine-3-carbonitriles.

Abstract

A three-component condensation of aromatic aldehydes, cyanothioacetamide, and benzoyl-1,1,1-trifluoroacetone, involving the acyl cleavage of the latter, results in 4-aryl-2-thioxo-6-phenyl-1,2-dihydropyridine- 3-carbonitriles. Their alkylation was studied.