Synthesis of 2-[4-Aryl(hetaryl, cyclopropyl)thiazol-2-yl]-3-hetarylacrylonitriles by Recyclizations of 2,6-Diamino-4-hetaryl-4H-thiopyran-3,5-dicarbonitriles with α-Bromoketones.

Abstract

Recyclization of 2,6-diamino-4-hetaryl-4H-thiopyran-3,5-dicarbonitriles with α-bromoketones afforded 2-[4-aryl(hetaryl, cyclopropyl)thiazol-2-yl]-3-hetarylacrylonitriles.